Pharmacology Antiemetic Agents Practice Test 2026 – All-in-One Study Guide to Master Your Exam!

Scopolamine is commonly prescribed for motion sickness due to its effectiveness as an anticholinergic agent. It works by blocking the action of acetylcholine, a neurotransmitter that can stimulate the vestibular system in the inner ear, which is responsible for balance and spatial orientation. When individuals are in motion, inappropriate signals can be sent to the brain, leading to nausea and vomiting. Scopolamine, often administered in the form of a transdermal patch, helps to prevent these symptoms by inhibiting the signals that contribute to motion sickness, making it particularly useful for travel-related conditions.

Other medications listed, while they can also have antiemetic properties, do not specifically target motion sickness to the extent that scopolamine does. For example, metoclopramide primarily acts as a prokinetic and is more effective for gastric issues rather than vestibular disturbances. Promethazine and hydroxyzine are effective antihistamines but are not the first-line treatments for motion sickness. Thus, scopolamine remains the preferred choice for managing this type of nausea.